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PAPERS

15/03/2013

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balzano@itis-usa.org

 

Stimulation of the Brain with Radiofrequency Electromagnetic Field Pulses Affects Sleep-Dependent Performance Improvement

Caroline Lustenberger, Manuel Murbach, Roland Dürr, Marc R. Schmid, Niels Kuster, Peter Achermann, and Reto Huber, Brain Stimulation, Volume 6, Issue 5, pp. 805-811, September 2013, online February 26, 2013

 
PAPERS

11/03/2013

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balzano@itis-usa.org

 

Whole-Body and Local RF Absorption in Human Models as a Function of Anatomy and Position within 1.5T MR Body Coil

Manuel Murbach, Esra Neufeld, Wolfgang Kainz, Klaas P. Pruessmann, and Niels Kuster, Magnetic Resonance in Medicine, Volume 71, Issue 2, pp. 839-845, February 2014, online February 25, 2013

 
PAPERS

25/02/2013

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balzano@itis-usa.org

 

No Increased Sensitivity in Brain Activity of Adolescents Exposed to Mobile Phone-Like Emissions

Sarah P. Loughran, Dominik Benz, Marc Schmid, Manuel Murbach, Niels Kuster, and Peter Achermann, Clinical Neurophysiology, Volume 124, Issue 7, pp. 1303-1308, July 2013, online February 20, 2013

 
Thermal Tissue Damage Model Analyzed for Different Whole-Body SAR and Scan Durations for Standard MR Body Coils
19/02/2013

Thermal Tissue Damage Model Analyzed for Different Whole-Body SAR and Scan Durations for Standard MR Body Coils

Manuel Murbach, Esra Neufeld, Myles Capstick, Wolfgang Kainz, David O. Brunner, Theodoros Samaras, Klaas P. Pruessmann, and Niels Kuster, Magnetic Resonance in Medicine, Volume 71, Issue 1, pp. 421-431, January 2014, online February 14, 2013

This article investigates the thermal safety of magnetic resonance imaging (MRI) by estimating the transient local tissue heating both in a 1.5T MRI system and in four anatomical human models in different Z-positions with and without local thermoregulation. To determine the effective thermal stress of the tissues, the thermal dose model "cumulative equivalent minutes at 43°C" (CEM43) was applied. This model allows predicting thermal tissue damage risk and identifying potentially hazardous MR scan-scenarios. The numerical results were validated by B1+ and skin temperature measurements. Under continuous exposure conditions at the guideline limit value, peak tissue temperatures of up to 42.8°C were computed for the thermoregulated model. When applying tissue-specific damage thresholds, adverse effects cannot be excluded after 25 min of scanning if the current scanning limits are fully exploited. As realistic exposures are considerably below the maximum levels allowed, the results are found to be consistent with the history of safe use in MR scanning, but not with current safety guidelines. For future safety concepts, we suggest to use thermal dose models instead of temperatures or SAR. Special safety concerns for patients with impaired thermoregulation (e.g., elderly or diabetic patients) should be addressed. 

The scientific and technical impact of this study can be summarized as:

  • Demonstration of the accurate translation of different MRI exposure scenarios to transient temperature increases in realistic human models and various scanning positions.
  • Modeling of realistic local thermoregulation.
  • Application of the thermal dose model (CEM43) and estimation of the maximum MR scan times tolerable before causing potential thermal tissue damage.
  • Numerical results are found to be consistent with the history of safe use in MR scanning.
  • Simulation models were validated with skin-temperature measurements in one healthy subject.
PAPERS

18/02/2013

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Analysis of Human Brain Exposure to Low-Frequency Magnetic Fields: A Numerical Assessment of Spatially Averaged Electric Fields and Exposure Limits

Xi Lin Chen, Stefan Benkler, Nicholas Chavannes, Valerio De Santis, Jurriaan Bakker, Gerard van Rhoon, Juan Mosig, and Niels Kuster, Bioelectromagnetics, Volume 34, Issue 5, pp. 375-384, July 2013, February 12, 2013

 
PAPERS

31/01/2013

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balzano@itis-usa.org

 

Influence of GSM Signals on Human Peripheral Lymphocytes: Study of Genotoxicity

Petra Waldmann, Susanne Bohnenberger, Rüdiger Greinert, Beate Hermann-Then, Anja Heselich, Stefanie J. Klug, Jochem Koenig, Kathrin Kuhr, Niels Kuster, Mandy Merker, Manuel Murbach, Dieter Pollet, Walter Schadenboeck, Ulrike Scheidemann-Wesp, Britt Schwab, Beate Volkmer, Veronika Weyer, and Maria Blettner, Radiation Research, Volume 179, Issue 4, pp. 243-253, April 2013, online January 14, 2013

 
PAPERS

28/01/2013

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Cell Type-Dependent Induction of DNA Damage by 1800 MHz Radiofrequency Electromagnetic Fields Does Not Result in Significant Cellular Dysfunctions

Shanshan Xu, Guangdi Chen, Chunjing Chen, Chuan Sun, Danying Zhang, Manuel Murbach, Niels Kuster, Qunli Zeng, and Zhengping Xu, PLoS ONE, Volume 8, Issue 1, online ahead of print January 23, 2013

 
 
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